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1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE CAS:85909-08-6

1-(tert-Butyloxycarbonyl)-2-pyrrolidone is mostly a white crystalline powder with stable chemical properties. It is a crucial intermediate in organic synthesis. Its unique molecular structure gives it good reactivity. In the pharmaceutical field, it is often used to synthesize various drug molecules, assist in the development of innovative drugs, and improve the stability and activity of drugs. In materials science, it can also participate in the preparation of high-performance materials, effectively improve the mechanical properties and processing properties of materials, and provide strong support for the development of related industries.

    ZhonghanProduct Overview

    1-(tert-Butyloxycarbonyl)-2-pyrrolidone occupies an important position in organic chemistry and related industries and is a compound with wide application value.

    ZhonghanStructural formula

    Molecular formula

     C9H15NO3

    Molecular weight

     185.22

    Boiling point

     100-105 °C/0.5 mmHg (lit.)

    Density

     1.086 g/mL at 25 °C (lit.)

    Form

     Oily

    Color

     transparent colorless to brown

    Refractive index

     n20/D 1.466 (lit.)

    Storage conditions

     Keep in dark place, Sealed in dry, Room Temperature

    Solubility

     soluble in chloroform and methanol

    Acidity coefficient

     -2.21±0.20 (Predicted)

     

    ZhonghanPhysical properties

    1. Appearance: It is a white crystalline powder under normal conditions, with stable properties, easy to store and transport, and not prone to deterioration under normal environmental conditions;

    2. Melting point: Generally between 50-54°C. This melting point characteristic has a key guiding significance for temperature control during its production, processing and application;

    3. Solubility: It is soluble in common organic solvents such as dichloromethane, ethyl acetate, etc., and slightly soluble in water. This solubility characteristic determines its applicability in different reaction systems, enabling it to play an important role in organic synthesis reactions.

    ZhonghanApplication Areas

    1. Pharmaceutical synthesis: As a key pharmaceutical intermediate, it plays an indispensable role in the synthesis routes of many drugs. For example, in the preparation process of some new antibacterial drugs, nervous system drugs and cardiovascular drugs, it can introduce key structural fragments through specific chemical reactions, thereby optimizing the structure of drug molecules, improving the efficacy of drugs, reducing toxic side effects, and enhancing the stability and bioavailability of drugs.

    2. Materials Science: In the research and development and production of high-performance polymer materials, 1-(tert-butylcarboxyl)-2-pyrrolidone can be used as a functional monomer to participate in polymerization reactions. By cleverly designing the polymerization process, it can be introduced into the main chain or side chain of the polymer, giving the material unique properties, such as improving the flexibility of the material, improving the thermal stability and mechanical strength of the material, etc., making it widely used in high-end fields such as aerospace, automobile manufacturing, and electronic appliances.

    3. Organic synthesis: In the field of organic synthetic chemistry, it is an important building block for building complex organic molecules. Using the active sites in its molecular structure, a series of functional group transformation reactions can be carried out, such as nucleophilic substitution, addition reaction, etc., which provides an effective way to synthesize organic compounds with specific structures and functions and promotes the development of organic synthetic chemistry.

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